HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178454059, compound → HCID 178511693, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178454059 | HCID 178454059 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178511693 | HCID 178511693 | 100.1% |
Reaction Steps
50 mg (0.13 mmol) cis-[4-(5-Chloro-isoquinolin-6-yloxy)-cyclohexyl]carbamic acid tert-butyl ester (12) were dissolved in ethanol/2N HCl (1:1) and stirred at room temperature until complete conversion could be detected (LCMS). Evaporation of the solvent furnished 36 mg of the title compound as hydrochloride. Rt=0.71 min (Method #1). Detected mass: 277.2/279.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710228B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-6520a7053e1141a6ae409c793a561c88 |
| Source note | uspto-grants-2014_04 |