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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370728Generated: October 29, 2026

HCID 178454059, compound → HCID 178511693, compound

https://huagongshe.com/reaction/2370728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178454059HCID 178454059—
SolventEthanolHCID 702—
ProductHCID 178511693HCID 178511693100.1%

Reaction Steps

50 mg (0.13 mmol) cis-[4-(5-Chloro-isoquinolin-6-yloxy)-cyclohexyl]carbamic acid tert-butyl ester (12) were dissolved in ethanol/2N HCl (1:1) and stirred at room temperature until complete conversion could be detected (LCMS). Evaporation of the solvent furnished 36 mg of the title compound as hydrochloride. Rt=0.71 min (Method #1). Detected mass: 277.2/279.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710228B2
Source datasetuspto-grants-2014_04
ORD IDord-6520a7053e1141a6ae409c793a561c88
Source noteuspto-grants-2014_04