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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370740Generated: October 30, 2026

7-Chloro-6-fluoroisoquinoline → HCID 178454055, compound

https://huagongshe.com/reaction/2370740

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-6-fluoroisoquinolineHCID 53418922—
ReactantHCID 178418813HCID 178418813—
ReactantHCID 178454060HCID 178454060—
ProductHCID 178454055HCID 178454055—

Reaction Steps

Starting with 7-chloro-6-fluoro-isoquinoline (6) and cis-(4-hydroxy-cyclohexyl)-carbamic acid tert-butyl ester, the title compound was prepared by the protocol described for trans-[4-(5-chloro-isoquinolin-6-yloxy)-cyclohexyl]-carbamic acid tert-butyl ester (10). Rt=1.07 min (Method #4). Detected mass: 377.2/379.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710228B2
Source datasetuspto-grants-2014_04
ORD IDord-3f82a9a00f9a4891beb1189a9964cfaf
Source noteuspto-grants-2014_04