HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoroisoquinoline → HCID 57646988, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoroisoquinoline | HCID 21889847 | — |
| Reactant | HCID 59268525 | HCID 59268525 | — |
| Product | HCID 57646988 | HCID 57646988 | — |
Reaction Steps
Cyclisation of N-(2,2-dimethoxy-ethyl)-4-methyl-N-(3,4,5-trifluoro-benzyl)-benzene-sulfonamide (100) by the method described for 6-fluoro-isoquinoline (5) gave the desired isoquinoline, which was isolated as trifluoro acetate after final purification by prep. HPLC. Rt=1.15 min (Method #1). Detected mass: 184.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710228B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-169b2ec061584f848101a3e6a3bb1aa8 |
| Source note | uspto-grants-2014_04 |