Methanol → HCID 178499561, compound

Participants

Reaction Steps

5.0 g (30.75 mmol) of 4-imidazoleacetic acid were dissolved in 50 ml of methanol and then 5.6 ml (76.87 mmol) of thionyl chloride were added. The resulting solution was heated under reflux for 4 h and, after cooling, evaporated to dryness. Drying under reduced pressure afforded 5.3 g of the desired product in the form of a pale yellow solid.

Provenance & Evidence