反应详情

A solution of 6-tert-butyl 2-ethyl 1-benzofuran-2,6-dicarboxylate (490 mg, 1.68 mmol) in ethanol (15 ml) was admixed with sodium hydroxide solution (3.36 ml, 1 M) and heated under reflux for 2 h. The cooled solution was added to ice-cooled hydrochloric acid (1 M), and the precipitate was filtered off with suction, washed with a little water and dried under reduced pressure.

1. temperatureheated
2. temperatureunder reflux for 2 h
3. additionThe cooled solution was added to ice-
4. filtrationthe precipitate was filtered off with suction
5. washwashed with a little water
6. customdried under reduced pressure