Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | HCID 14127593 | HCID 14127593 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14127620 | HCID 14127620 | — |
Reaction Steps
3.54 g of 8-(2-aminophenoxy)quinoline are dissolved in 70 ml of dichloromethane, and a solution of 3.17 g of 4-chlorobenzenesulphonyl chloride in 30 ml of dichloromethane is added at 25° C. After 1 hour, 2.42 ml of pyridine are added, and the mixture is stirred for 15 hours at 25° C. After removal of the solvent by evaporation, the residue is stirred with water. The product is filtered off and recrystallized from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05093340 |
|---|
| Source dataset | uspto-grants-1992_03 |
|---|
| ORD ID | ord-8e4533b13085418abdfe82b663b55264 |
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| Source note | uspto-grants-1992_03 |
|---|
