Ethanol → HCID 19907417, compound

HRID 2371520Notes

Reaction equation

HRID 2371520 reaction equation
[CH2:1]([N:3]([CH2:21][CH3:22])[CH2:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][CH2:15][N:16]([CH2:19][CH3:20])[CH2:17][CH3:18])=[CH:9][CH:8]=1)[CH3:2].[CH2:23]([I:25])[CH3:24].[CH2:26](O)[CH3:27]>>[I-:25].[I-:25].[CH2:19]([N+:16]([CH2:23][CH3:24])([CH2:17][CH3:18])[CH2:15][CH2:14][CH2:13][C:10]1[CH:9]=[CH:8][C:7]([CH2:6][CH2:5][CH2:4][N+:3]([CH2:26][CH3:27])([CH2:1][CH3:2])[CH2:21][CH3:22])=[CH:12][CH:11]=1)[CH3:20]

Participants

4

Reactant 3

HCID 702EthanolHCID 6340IodoethaneHCID 19907373N1,N1,N4,N4-Tetraethyl-1,4-benzenedipropanamine

Product 1

HCID 19907417HCID 19907417, compound

Procedure

304 mg of 1,4-bis(3-diethylaminopropyl)benzene was dissolved in 2.5 ml of absolute ethanol, and after dropwise addition of 1.56 g of ethyl iodide, the mixture was refluxed for 1.5 hours in dark. After cooling, ethanol was partially removed under reduced pressure, the resulting crystal was filtered, quickly washed with ethanol and dried in vacuo to obtain 461 mg of the title compound as a colorless crystal.

Workup

  1. temperaturethe mixture was refluxed for 1.5 hours in dark
  2. temperatureAfter cooling
  3. customethanol was partially removed under reduced pressure
  4. filtrationthe resulting crystal was filtered
  5. washquickly washed with ethanol
  6. customdried in vacuo

Sources & evidence

ORD record
ord-f56d38cc919b4907a66efe008234e97d
Source dataset
uspto-grants-1992_03
Patent number
US05093370

Reaction notes

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