2-Chloroethanol → HCID 19907383, compound

Participants

Reaction Steps

To 5.0 g of p-xylylene dichloride was added 25 ml of 2-chloroethanol, and the mixture was refluxed for 24 hours. After the reaction, 2-chloroethanol was removed under reduce pressure at 100° C. The residue was applied to a silica gel column and eluted with hexane/chloroform (1:1) as eluent, and a relevant fraction was further purified by distillation to obtain 2.44 g of the title compound as a colorless liquid.

Provenance & Evidence