Propylamine → N-(2-Phenoxyethyl)propylamine

HRID 2371586Notes

Reaction equation

HRID 2371586 reaction equation
[O:1]([CH2:8][CH2:9]Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:11]([NH2:14])[CH2:12][CH3:13]>C(O)C.O>[CH2:11]([NH:14][CH2:9][CH2:8][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:12][CH3:13]

Participants

4

Reactant 2

HCID 7852PropylamineHCID 12156Benzene, (2-chloroethoxy)-

Product 1

HCID 6453152N-(2-Phenoxyethyl)propylamine

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

the 2-phenoxyethyl chloride is reacted with n-propyl-amine in the presence of an ethanol-water mixed solvent at a temperature of from 100° C. to 110° C., to form N-n-propyl-N-2-phenoxyethyl amine;

Sources & evidence

ORD record
ord-11d633c4f20142d3b8960b75498ec3dd
Source dataset
uspto-grants-1992_03
Patent number
US05093526

Reaction notes

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