HRID2371622

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCc1c(OCCCOc2ccc(Cl)cc2)ccc2c1OC(CCC(=O)OCC)(CCC(=O)OCC)CC2=O

HCID15157438

未命名化合物

结构：CCCc1c(OCCCOc2cccc(C(F)(F)F)c2)ccc2c1OC(CCC(=O)OCC)(CCC(=O)OCC)CC2=O

HCID15157453

未命名化合物

PRODUCTS

生成物

结构：CCCc1c(OCCCOc2cccc(C(F)(F)F)c2)ccc2c1OC(CCC(=O)O)(CCC(=O)O)CC2=O

HCID15157454

未命名化合物

收率 60.4%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

The title compound was prepared by the method of Example 22 except that the title product of Example 36 (487 mg) was substituted for the title product of Example 21. Trituration with diethyl ether produced 267 mg of the titled compound as a solid, m.p. 129°-129.5° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-165111bd7b0b42c9bb139f9242392640
来源数据集: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05093353
来源说明: uspto-grants-1992_03

反应 SMILES

[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][C:10]([O:15][CH2:16][CH2:17][CH2:18][O:19][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:28])[F:27])[CH:21]=3)=[C:11]([CH2:12][CH2:13][CH3:14])[C:6]=2[O:5][C:4]([CH2:37][CH2:38][C:39]([O:41]CC)=[O:40])([CH2:30][CH2:31][C:32]([O:34]CC)=[O:33])[CH2:3]1.ClC1C=CC(OCCCOC2C=CC3C(=O)CC(CCC(OCC)=O)(CCC(OCC)=O)OC=3C=2CCC)=CC=1>C(OCC)C>[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][C:10]([O:15][CH2:16][CH2:17][CH2:18][O:19][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:27])[F:28])[CH:21]=3)=[C:11]([CH2:12][CH2:13][CH3:14])[C:6]=2[O:5][C:4]([CH2:37][CH2:38][C:39]([OH:41])=[O:40])([CH2:30][CH2:31][C:32]([OH:34])=[O:33])[CH2:3]1