diethyl 3,4-dihydro-7-[3-(4-chlorophenoxy)propoxy]-4-oxo-8-propyl-2H-1-benzopyran-2,2-dipropanoate → 3,4-dihydro-4-oxo-8-propyl-7-[3-[3-(trifluoromethyl)phenoxy]propoxy]-2H-1-benzopyran-2,2-dipropanoic acid

Participants

Reaction Steps

The title compound was prepared by the method of Example 22 except that the title product of Example 36 (487 mg) was substituted for the title product of Example 21. Trituration with diethyl ether produced 267 mg of the titled compound as a solid, m.p. 129°-129.5° C.

Provenance & Evidence