HRID237164

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID93865

2-(tert-Butoxycarbonyloximino)-2-phenylacetonitrile

C13H14N2O3

HCID45263723

Benzeneacetic acid, 3-(aminomethyl)-, hydrochloride (1:1)

C9H12ClNO2

HCID53407881

[4-(Aminomethyl)phenyl]acetic acid--hydrogen chloride (1/1)

C9H12ClNO2

PRODUCTS

生成物

HCID2755930

(3-{[(tert-Butoxycarbonyl)amino]methyl}phenyl)acetic acid

C14H19NO4

PROCEDURE

实验过程

Substitution of an equivalent amount of 3-aminomethylphenylacetic acid hydrochloride for 4-aminomethylphenylacetic acid hydrochloride in the reaction with 2-t-butoxycarbonyloxyimino-2-phenylacetonitrile described in Example 54 gave 3-(N-t-butoxycarbonylaminomethyl)phenylacetic acid, m.p. 95°-96.5°.