Sodium Hydroxide → HCID 67914037, compound

Participants

Reaction Steps

A mixture of 4.20 g of ethyl 4-(dibenz[b,e]oxepin-11(6H)-ylidene)-1-piperidinevalerate hydrochloride, 14.5 ml of 2N sodium hydroxide aqueous solution and 40 ml of methanol was refluxed for 1 hr and concentrated. Water was added to the residue, adjusted to pH 2 with 10% hydrochloric acid. The precipitate was collected by filtration and washed with water and ether to give 3.92 g of colorless crystals, which were recrystallized from water to give 3.08 g of colorless prisms, mp 304°-306° C. (dec.).

Provenance & Evidence