Sodium Hydroxide → HCID 24837049, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1.32 g (33 mmoles) of NaOH in 32 ml of methanol, is added under stirring at a temperature of 10° C., with 3.19 g (10 mmoles), of cis-2-[[N-[2-methoxy-2-oxoethyl]-N-phenylamino]carbonyl]-cyclohexanecarbo xylic acid (prepared from the anhydride of the cis-1,2-cychlohexanbicarboxylic acid and methyl N-phenyl-aminoacetate according to a process like that disclosed in the example 2), and then with 0.764 g (11 mmoles) of hydroxylamine hydrochloride. The resulting suspension is maintained under stirring at 15° C. for 6 hours, then at rest for the night.

Provenance & Evidence