Hydrochloric Acid → HCID 19905512, compound

HRID 2371975Notes

Reaction equation

HRID 2371975 reaction equation
C[O:2][C:3](=[O:25])[CH2:4][CH2:5][CH2:6][NH:7][C:8](=[O:24])[CH:9]([CH2:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:10][CH2:11][C:12]([O:14]C)=[O:13].[OH-].[Na+].Cl>CO>[C:12]([CH2:11][CH2:10][CH:9]([CH2:16][CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)[C:8]([NH:7][CH2:6][CH2:5][CH2:4][C:3]([OH:25])=[O:2])=[O:24])([OH:14])=[O:13]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 53916629HCID 53916629, compound

Product 1

HCID 19905512HCID 19905512, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To the solution of 150 mg of N-(4-methoxycarbonyl-2-phenethylbutyryl)-4-aminobutyric acid methyl ester in 3 ml of methanol is added 1.0 ml of 1N sodium hydroxide and stirred for 4 hours at room temperature. The mixture is acidified with 1.5 ml of 1N hydrochloric acid, and concentrated. The solid is collected and washed with water to yield N-(4-carboxy-2-phenethyl-butyryl)-4-aminobutyric acid.

Workup

  1. concentrationconcentrated
  2. customThe solid is collected
  3. washwashed with water

Sources & evidence

ORD record
ord-9d374ea139c049599d450ceb892e8423
Source dataset
uspto-grants-1992_03
Patent number
US05096925

Reaction notes

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