3-Methylbenzoyl chloride → HCID 14366279, compound

HRID 2371983Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5](Cl)=[O:6].C[O:12][P:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([P:13]1(=[O:12])[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1)=[O:6]

Participants

Conditions

Temperature: 115 °C

Procedure

46.6 g (0.3 mol) of 3-methylbenzoyl chloride were warmed to 85° C. under a nitrogen atmosphere. 69 g (0.3 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin were added dropwise while stirring. The temperature was then increased in steps to 115° C. When the reaction was complete, 50 ml of toluene were added at room temperature. After crystallization, 85 g (84% of theory) of the abovementioned compound of melting point 108° to 111° C. were obtained.

Workup

customAfter crystallization, 85 g (84% of theory) of the abovementioned compound of melting point 108° to 111° C.
customwere obtained

Sources & evidence

ORD record: ord-31a77cc2be784d448c2fe850b5debb09
Source dataset: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05096935

Reaction notes

Loading…