3,5-Dimethylbenzoyl Chloride → HCID 14366285, compound

HRID 2371987Notes

Reaction equation

HRID 2371987 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5](Cl)=[O:6].C[O:13][P:14]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1>CC(C)=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5]([P:14]1(=[O:13])[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1)=[O:6]

Participants

4

Reactant 2

HCID 810883,5-Dimethylbenzoyl ChlorideHCID 114361486-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin

Product 1

HCID 14366285HCID 14366285, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
115 °C

Procedure

67.4 g (0.4 mol) of 3,5-dimethylbenzoyl chloride were warmed to 80° C. under a nitrogen atmosphere. 92 g (0.4 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. The temperature during the addition was increased in steps to 115° C. When the reaction was complete, 50 ml of acetone were added at room temperature. After crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C. were obtained.

Workup

  1. additionThe temperature during the addition
  2. customAfter crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C.
  3. customwere obtained

Sources & evidence

ORD record
ord-356015debd6a47fb9674b9834b98e589
Source dataset
uspto-grants-1992_03
Patent number
US05096935

Reaction notes

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