2,6-Dimethoxybenzoyl chloride → HCID 14366290, compound

HRID 2371991Notes

Reaction equation

HRID 2371991 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[C:4]=1[C:5](Cl)=[O:6].C[O:15][P:16]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[C:19]2[CH:26]=[CH:27][CH:28]=[CH:29][C:18]=2[O:17]1>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[C:4]=1[C:5]([P:16]1(=[O:15])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[C:19]2[CH:26]=[CH:27][CH:28]=[CH:29][C:18]=2[O:17]1)=[O:6]

Participants

4

Reactant 2

HCID 748102,6-Dimethoxybenzoyl chlorideHCID 114361486-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin

Product 1

HCID 14366290HCID 14366290, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
125 °C

Procedure

60.1 g (0.3 mol) of 2,6-dimethoxybenzoyl chloride were warmed to 85° C. under a nitrogen atmosphere. 69 g (0.3 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. The temperature was then slowly increased to 125° C. When the reaction was complete and after cooling, 150 ml of toluene were added. After crystallization, 99 g (87% of theory) of the abovementioned compound of melting point 96° to 98° C. were obtained.

Workup

  1. temperatureafter cooling
  2. customAfter crystallization, 99 g (87% of theory) of the abovementioned compound of melting point 96° to 98° C.
  3. customwere obtained

Sources & evidence

ORD record
ord-5ab2658461fd4abeaf09cc69d36c1b2a
Source dataset
uspto-grants-1992_03
Patent number
US05096935

Reaction notes

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