Hydrazine hydrate (1:1) → 3-Amino-1-(3,5-difluorophenyl)urea

Participants

Reaction Steps

To a solid 100 mg of O-phenyl 3,5-difluorophenylcarbamate 0.7 mL of hydrazine monohydrate was added. After stirring for 3 h at room temperature a white solid is collected by filtration, washed with water and ether. Removal of traces of the solvents in vacuo gives 4-(3,5-difluorophenyl)-semicarbazide: m.p. 177°-179° C.

Provenance & Evidence