Sodium Iodide → HCID 67915251, compound

HRID 2372286Notes

Reaction equation

HRID 2372286 reaction equation
[Cl:1][CH:2]1[CH2:6][N:5]([CH3:7])[C:4](=[S:8])[N:3]1[CH3:9].Cl[CH2:11][C:12](=[O:14])[CH3:13].[I-].[Na+]>CC(C)=O>[Cl-:1].[Cl:1][C:2]1[N:3]([CH3:9])[CH:4]([S:8][CH2:11][C:12](=[O:14])[CH3:13])[NH+:5]([CH3:7])[CH:6]=1

Participants

5

Reactant 3

HCID 5238Sodium IodideHCID 6571ChloroacetoneHCID 54006717HCID 54006717, compound

Product 1

HCID 67915251HCID 67915251, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 1.00 gram (0.0062 mol) of 4-chloro-1,3-dimethyl-imidazoline-2-thione in 180 mL of acetone was added 0.569 g (0.0062 mol) of chloroacetone and a small crystal of sodium iodide. The mixture was stirred overnight at room temperature whereupon a product precipitated. The latter was recovered by filtration and recrystallized from isopropyl alcohol-hexane to obtain purified 4-chloro-1,3-dimethyl-2[-(2-oxopropyl)thio]-1H-imidazolium chloride, m.p. 134°-136° C.

Workup

  1. customprecipitated
  2. filtrationThe latter was recovered by filtration
  3. customrecrystallized from isopropyl alcohol-hexane
  4. customto obtain
  5. custompurified 4-chloro-1,3-dimethyl-2[-(2-oxopropyl)thio]-1H-imidazolium chloride, m.p. 134°-136° C.

Sources & evidence

ORD record
ord-146efa6e52644b9983beed5291c1d6a0
Source dataset
uspto-grants-1992_03
Patent number
US05098707

Reaction notes

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