Allylamine → HCID 13853883, compound

HRID 2372341Notes

Reaction equation

[Cl:1][C:2]1[C:3](=[O:23])[N:4]([C:19]([CH3:22])([CH3:21])[CH3:20])[N:5]=[CH:6][C:7]=1[NH:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]([OH:18])=O)=[CH:12][CH:11]=1.[CH2:24]([NH2:27])[CH:25]=[CH2:26]>>[Cl:1][C:2]1[C:3](=[O:23])[N:4]([C:19]([CH3:20])([CH3:22])[CH3:21])[N:5]=[CH:6][C:7]=1[NH:8][CH2:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]([NH:27][CH2:24][CH:25]=[CH2:26])=[O:18])=[CH:14][CH:15]=1

Participants

Reactant 2

HCID 7853Allylamine

HCID 13853865HCID 13853865, compound

Product 1

HCID 13853883HCID 13853883, compound

Procedure

The compounds as identified in Table 13 were prepared in the synthetic manner and after-treatment similar to those in Example 6 except that the carboxylic acids with R1, R2, R3, Y1, Y2 and Y3 as identified in Table 13 were used instead of the starting 4-chloro-5-(4-carboxybenzylamino)-2-t-butyl-3(2H)pyridazinone used in Example 6, and the amines with Y1, Y2 and Y3 as identified in Table 13 were used instead of the starting allylamine. In the NMR data, only the characteristic absorptions are given in Table 13.

Workup

customwere prepared in the synthetic manner

Sources & evidence

ORD record: ord-51cb048ae6864d0ab755cccc39087497
Source dataset: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05098900

Reaction notes

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