HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2372388Generated: October 31, 2026
Methylamine → N-Methyl-(7-isopropoxycarbonyl-6-methyl-5,6-dihydropyrrolo[2,1-b]thiazol-3-yl)acetamide
https://huagongshe.com/reaction/2372388
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl (7-isopropoxycarbonyl-6-methyl-5,6-dihydropyrrolo[2,1-b]thiazol-3-yl)acetate | HCID 86745570 | — |
| Product | N-Methyl-(7-isopropoxycarbonyl-6-methyl-5,6-dihydropyrrolo[2,1-b]thiazol-3-yl)acetamide | HCID 19903349 | — |
Reaction Steps
3.3 g of ethyl (7-isopropoxycarbonyl-6-methyl-5,6-dihydropyrrolo[2,1-b]thiazol-3-yl)acetate was added to 60 ml of a 40% aqueous solution of monomethylamine and stirred at 20° C. for 24 hours. The precipitate was collected by filtration, washed with water, dried, and recrystallized from ethanol. Thus 2.2 g of the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05098919 |
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| Source dataset | uspto-grants-1992_03 |
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| ORD ID | ord-c6f27ea04ff14526819659f671fd965c |
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| Source note | uspto-grants-1992_03 |
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