Trifluoroacetic acid → HCID 67918790, compound

HRID 2372513Notes

Reaction equation

C([O:5][C:6](=[O:19])[CH2:7][N:8]([CH2:17][F:18])[C:9](=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)(C)(C)C.FC(F)(F)C(O)=O>>[F:18][CH2:17][N:8]([C:9](=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:7][C:6]([OH:19])=[O:5]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 19904580HCID 19904580, compound

Product 1

HCID 67918790HCID 67918790, compound

Procedure

Fluoromethylbenzoylglycine t-butyl ester was treated with trifluoroacetic acid for one hour, and the product was purified by thin layer chromatography. Mp 233°-235°.

Workup

customthe product was purified by thin layer chromatography

Sources & evidence

ORD record: ord-64f99f48b2ae489bbe32f4e8ba95da92
Source dataset: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05098996

Reaction notes

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