2-Oxobutanoic Acid → HCID 22827896, compound

HRID 2372597Notes

Reaction equation

HRID 2372597 reaction equation
[NH2:1][C@H:2]([C:4]([N:6]([CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)[CH2:7][C:8]([OH:10])=[O:9])=[O:5])[CH3:3].O=[C:21]([CH2:25][CH3:26])[C:22]([OH:24])=[O:23].C([BH3-])#N.[Na+]>>[C:22]([CH:21]([NH:1][C@H:2]([C:4]([N:6]([CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)[CH2:7][C:8]([OH:10])=[O:9])=[O:5])[CH3:3])[CH2:25][CH3:26])([OH:24])=[O:23]

Participants

4

Reactant 3

HCID 582-Oxobutanoic AcidHCID 5003444Sodium cyanoborohydrideHCID 13132286HCID 13132286, compound

Product 1

HCID 22827896HCID 22827896, compound

Procedure

By using 1.0 g of L-alanyl-N-(indan-2-yl)glycine, 6.0 g of 2-oxo-butyric acid and 1.0 g of sodium cyanoborohydride in a similar procedure to that of Example 1, there can be obtained 0.4 of N-(1-carboxypropyl)-L-alanyl-N-(indan- 2-yl)glycine as colorless powder.

Sources & evidence

ORD record
ord-993dfbbf5da548ee98cec0c139ff5d05
Source dataset
uspto-grants-1992_03
Patent number
US05098892

Reaction notes

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