HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylazetidin-3-ol → 3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-1-phenyl-azetidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylazetidin-3-ol | HCID 22436526 | — |
| Reactant | 5-Bromo-2-(3-fluoro-benzyloxy)-phenol | HCID 67348159 | — |
| Product | 3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-1-phenyl-azetidine | HCID 58405175 | — |
Reaction Steps
Prepared by the procedure of Example 163 using 5-bromo-2-(3-fluoro-benzyloxy)-phenol and 1-phenyl-azetidin-3-ol. MS (ESI): mass calcd. for C22H19BrFNO2, 427.1; m/z found, 428.2 [M+H]+. 1H NMR (CDCl3): 7.34-6.47 (m, 12H), 5.11-5.03 (m, 3H), 4.36-4.28 (m, 2H), 3.98-3.91 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642583B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-0957b28c513c47f9bfcffb88fe74ffac |
| Source note | uspto-grants-2014_02 |