Morpholine → HCID 19902175, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-12-fluoro-2,3-dihydrodiimidazo[1,5-a:1',2'-c]quinazoline (0.25 g, 0.7 mmol) in a mixture of morpholine (10 ml) and DMF (15 ml) was heated at 120° C. for 6 h. Then the solvent was evaporated and the solid residue was triturated with 10 ml of water, filtered off and dried to give the title compound as pale crystals, m.p. 217°-220° C. Yield 0.16 g (57%). (Compound 46).

Provenance & Evidence