HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinecarboxylic acid → 1-Acetylpiperidine-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinecarboxylic acid | HCID 3773 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Product | 1-Acetylpiperidine-4-carboxylic acid | HCID 117255 | 79% |
Reaction Steps
100 g of 4-piperidinecarboxylic acid and 400 ml of acetic anhydride are mixed. The mixture is brought to reflux for 2 hours and then left overnight at room temperature. The reaction medium is concentrated and the residue is ground with ethyl ether, filtered off and then washed with ethyl ether to obtain the expected compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05100902 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-230d6e1cdadc44d2a10a6a5f42108d9a |
| Source note | uspto-grants-1992_03 |