Dimethylformamide → HCID 19761210, compound

HRID 2372754Notes

Reaction equation

HRID 2372754 reaction equation
[C:1]([CH:3]([CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]2[O:14][CH2:15][O:16][C:9]=12)C(O)=O)#[N:2].CN(C)C=O>O>[C:1]([CH2:3][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]2[O:14][CH2:15][O:16][C:9]=12)#[N:2]

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 19761227HCID 19761227, compound

Product 1

HCID 19761210HCID 19761210, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
150 °C

Procedure

0.046 mole of the acid obtained in stage B is mixed with 19 ml of dimethylformamide and the mixture is then heated to 150° C. for 2 hours. The mixture is taken up with water and the product is extracted with ethyl ether. The organic phases are washed with sodium bicarbonate solution and then with water; they are dried and the solvent is evaporated off to obtain an oily residue.

Workup

  1. extractionthe product is extracted with ethyl ether
  2. washThe organic phases are washed with sodium bicarbonate solution
  3. customthey are dried
  4. customthe solvent is evaporated off
  5. customto obtain an oily residue

Sources & evidence

ORD record
ord-f8435b4b17f149b2bfad0f17923ed44e
Source dataset
uspto-grants-1992_03
Patent number
US05100902

Reaction notes

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