反应详情

24.0 g (152 mmol) 4-methoxy-2-thiophenecarboxylic acid were suspended in 250 ml thionyl chloride and heated for two hours under reflux. The excess thionyl chloride was then distilled off under vacuum. The crude product was quickly distilled off and crystallised out in the receiver.

1. temperatureheated for two hours
2. temperatureunder reflux
3. distillationThe excess thionyl chloride was then distilled off under vacuum
4. distillationThe crude product was quickly distilled off
5. customcrystallised out in the receiver