HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Methoxythiophene-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Methoxythiophene-2-carboxylic acid | HCID 12646619 | — |
| Product | 4-Methoxythiophene-2-carbonyl chloride | HCID 14721837 | — |
Reaction Steps
24.0 g (152 mmol) 4-methoxy-2-thiophenecarboxylic acid were suspended in 250 ml thionyl chloride and heated for two hours under reflux. The excess thionyl chloride was then distilled off under vacuum. The crude product was quickly distilled off and crystallised out in the receiver.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05100911 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-0fb81332dea545dab94f6c6b4b2eedaf |
| Source note | uspto-grants-1992_03 |