Hydrochloric Acid → HCID 21200841, compound

Participants

Reaction Steps

A mixture of 5.12 g (0.0187 mol) of 4-[(4-methoxyphenyl)sulfonyl]benzonitrile and 21.6 g of pyridinium hydrochloride is kept at 200° C. for 2 hours. After cooling, the reaction medium is hydrolyzed in a 1 N solution of hydrochloric acid. The precipitate formed is filtered off and rinsed with a 1 N solution of hydrochloric acid and then with water until the pH of the washings is neutral. 4.5 g (yield: 99%) of the expected product are thus obtained in the form of a gray solid.

Provenance & Evidence