反应详情

10 g of 3-hydroxy-4-nitro-phthalide are dissolved in 100 ml of tetrahydrofuran and hydrogenated at atmospheric pressure and at 20°-35° C. after adding 1 g of palladium on barium sulphate (5%). The catalyst is filtered off and the filtrate is concentrated. The evaporation residue is stirred with ether and filtered with suction. 5.8 g (68.5% of theory) of a colorless substance of melting point 280°-285° C. (dec.) are obtained.

1. filtrationThe catalyst is filtered off
2. concentrationthe filtrate is concentrated
3. filtrationfiltered with suction
4. custom5.8 g (68.5% of theory) of a colorless substance of melting point 280°-285° C. (dec.) are obtained