HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-n-Butyl-4-chloro-5-ethyl-6-methylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-n-Butyl-5-ethyl-6-methylpyrimidin-4(3H)-one | HCID 135625455 | — |
| Product | 2-n-Butyl-4-chloro-5-ethyl-6-methylpyrimidine | HCID 19902233 | — |
Reaction Steps
The pyrimidinone from Example 1 2-butyl-5-ethyl-6-methylpyrimidin-4(3H)-one is converted to the title compound upon treatment with phosphoryl chloride as described by Gabriel and Colman (Ber. 1899, 32, 2921) and by Marshall and Walker (J. Chem. Soc., 1951, 1004).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05100897 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-7fd8798c909940fa954a3d676f720547 |
| Source note | uspto-grants-1992_03 |