p-Toluenesulfonic acid → 6-(4-Trifluoromethylphenylthio)-3-hexen-2-one

HRID 2373047Notes

Reaction equation

HRID 2373047 reaction equation
O[CH:2]([CH2:7][CH2:8][S:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][CH:11]=1)[CH2:3][C:4](=[O:6])[CH3:5].C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[F:18][C:16]([F:17])([F:19])[C:13]1[CH:14]=[CH:15][C:10]([S:9][CH2:8][CH2:7][CH:2]=[CH:3][C:4](=[O:6])[CH3:5])=[CH:11][CH:12]=1

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 145344724-Hydroxy-6-(4-trifluoromethylphenylthio)2-hexanone

Product 1

HCID 572068326-(4-Trifluoromethylphenylthio)-3-hexen-2-one

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

0.3 Gram of 4-hydroxy-6-(4-trifluoromethylphenylthio)-2-hexanone was dissolved in 30 ml of toluene, and 0.004 g of p-toluenesulfonic acid was added thereto. The resulting mixture was refluxed for 30 minutes with stirring, allowed to cool and then treated in the same manner as in Production example 34. Thus, 6-(4-trifluoromethylphenylthio)-3-hexen-2-one was obtained (purity: 98.5%).

Workup

  1. temperatureThe resulting mixture was refluxed for 30 minutes
  2. temperatureto cool
  3. additiontreated in the same manner as in Production example 34

Sources & evidence

ORD record
ord-9d28970be9194682996e6443949482de
Source dataset
uspto-grants-1992_03
Patent number
US05101076

Reaction notes

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