2-[(4-Carboxyphenyl)thio]benzoic acid → 9-oxo-9H-Thioxanthene-2-carboxylic acid
Reaction equation
[S:1]([C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=O)[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1>CS(O)(=O)=O>[CH:4]1[C:3]2[C:13](=[O:15])[C:12]3[C:11](=[CH:19][CH:18]=[CH:17][CH:16]=3)[S:1][C:2]=2[CH:10]=[CH:9][C:5]=1[C:6]([OH:8])=[O:7]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 85 °C
Procedure
Next, thioxanthen-9-one-2-carboxylic acid was prepared. A mixture of 2,4′-thiobis(benzoic acid) (50 g, 182 mmol) and methansulfonic acid (600 mL) was heated at 85° C. for 5 h and then cooled to ambient. The reaction mixture was poured onto ice, and the resulting precipitate was collected, washed with water, and dried.
Workup
- temperaturecooled
- additionThe reaction mixture was poured onto ice
- customthe resulting precipitate was collected
- washwashed with water
- customdried
Sources & evidence
- ORD record
- ord-9ca513cf889f4ceeb4e12e102ad1a256
- Source dataset
- uspto-grants-2008_12
- Patent number
- US07459263B2
Reaction notes
Loading…