Acetic Acid → HCID 136352454, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5.0 g of olanzapine base in 150 ml acetone was added slowly 1.o6 g of acetic acid at room temperature and the mixture was stirred overnight at 4° C. The crystals were isolated by filtration, washed with 20 ml acetone and 20 ml of ether and dried overnight at 40° C. in vacuo. Yield: 3.32 g (56%).

Provenance & Evidence