Hydrochloric Acid → (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride

HRID 2373248Notes

Reaction equation

HRID 2373248 reaction equation
[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1.[ClH:21]>>[ClH:21].[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10378544(R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one

Product 1

HCID 68644147(R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride

Procedure

Using a known method, (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one was converted to a hydrochloride to give (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride.

Sources & evidence

ORD record
ord-e76e3a73302b450e9c1c266deb852e3a
Source dataset
uspto-grants-2008_12
Patent number
US07459465B2

Reaction notes

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