HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 59852576, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 59852552 | HCID 59852552 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 59852576 | HCID 59852576 | 104.4% |
Reaction Steps
To a solution of the preceding compound, (2S)-(5-Bromo-2-hydroxy-benzoylamino)-3-(4′-phenoxy-biphenyl-4-yl)-propionic acid methyl ester (10 mg, 18 μmol) in THF/MeOH was added aqueous LiOH, as described in General procedure C which, after work-up afforded the title compound, (2S)-(5-Bromo-2-hydroxy-benzoylamino)-3-(4′-phenoxy-biphenyl-4-yl)-propionic acid (10 mg ) LCMS for C28H22BrNO5: 531, 533.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459472B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-63e33e334c164a41a7d1763f2b8cd3ed |
| Source note | uspto-grants-2008_12 |