Triethylamine → HCID 57717668, compound

Participants

Reaction Steps

4-Methoxy-4′-trifluoromethyl-biphenyl-3-carboxylic acid [2-(3′-chloro-4′-fluoro-biphenyl-4-yl)-1-(R)-methoxymethyl-ethyl]-amide (45 mg) was prepared from 1-(3′-Chloro-4′-fluoro-biphenyl-4-ylmethyl)-2-methoxy-ethylamine hydrochloride salt (35 mg, 0.1 mmol) and 4-Methoxy-4′-trifluoromethyl-biphenyl-3-carbonyl chloride (32 mg, 0.1 mmol) in presence of triethyl amine (41 mg, 0.41 mmol) according to the general procedure M.

Provenance & Evidence