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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373861Generated: November 2, 2026

HCID 3730311, compound → HCID 72818345, compound

https://huagongshe.com/reaction/2373861

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 3730311HCID 3730311—
ReactantHCID 53436803HCID 53436803—
ProductHCID 72818345HCID 72818345—

Reaction Steps

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-benzoic acid (283 mg, 1.0 mmol) and 2-amino-3-(4′-trifluoromethyl-biphenyl-4-yl)-propionic acid methyl ester (360 mg, 1.0 mmol) following general procedure A. (580 mg) 1H-NMR(400 MHz, CD3COCD3): 3.24 (dd, 1H), 3.39 (dd, 1H), 3.74 (s, 3H), 4.98 (m, 1H), 6.64 (d, 1H), 7.50 (m, 2H), 7.60 (m, 2H), 7.69 (m, 3H), 7.78 (d, 2H), 7.88 (d, 2H), 7.98(m, 2H), 8.15 (m, 2H); LC/MS (m/z): 589 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459472B2
Source datasetuspto-grants-2008_12
ORD IDord-ec57ca60e8fd40c6a9b9b2e249b0f5c6
Source noteuspto-grants-2008_12