Hydrochloric Acid → HCID 86604614, compound

Participants

Reaction Steps

To a solution of C-(3-chloropyrazin-2-yl)-C-phenylmethylamine (1.582 g, 7.20 mmol) in 1,4-dioxane (≦5 mL), HCl (2 mL, 7.55 mmol, 4M soln. in 1,4-dioxane) was added and left for approx. 5 min. The reaction mixture was filtered and the solid was washed several times with 1,4-dioxane, yielding the title compound as a tan solid. Sample contains ≈0.1 eq. of 1,4-dioxane by 1H NMR; 1H NMR (d-MeOH, 400 MHz) δ 5.85 (s, 1H), 7.35 (s, 1H), 8.44 (d, J=2.4 Hz, 1H), 8.65 (d, J=2.4 Hz, 1H).

Provenance & Evidence