HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 59519199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 59519309 | HCID 59519309 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59519199 | HCID 59519199 | — |
Reaction Steps
A solution of 2-amino-4-(1-benzenesulfonyl-1H-indol-3-yl)-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester (80 mg, 0.17 mmol) in ethanol (6 ml) was heated to 65° C., 2M potassium hydroxide added (0.25 ml, 3 equiv.) and stirred overnight. Water was added and the volatile removed in vacuo. The solution was then neutralised and freeze dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642594B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-8eed4f7656b44eddb3ffc3e0a07a3bc3 |
| Source note | uspto-grants-2014_02 |