反应详情

A mixture of tert-butyl 6-(2-fluoro-4-nitrophenoxy)pyrimidin-4-yl(methyl)carbamate in 1:1 EtOH/MeOH (2 mL) was treated with PtO2 (10 mg) and the reaction mixture was stirred under a blanket of H2 (from a latex balloon) for 2 h. The reaction mixture was filtered and concentrated to give the desired product (30 mg, 75%) as a light brown solid. MS(ESI+) m/z 365.13 (M+H)+.

1. filtrationThe reaction mixture was filtered
2. concentrationconcentrated