Guanidine Hydrochloride → 1314911-69-7

HRID 2374209Notes

Reaction equation

HRID 2374209 reaction equation
[ClH:1].[CH3:2][CH:3]([CH2:6][NH2:7])[CH2:4][NH2:5].C[O-].[Na+].Cl.[NH2:12][C:13](N)=N>CO>[ClH:1].[CH3:2][CH:3]1[CH2:6][NH:7][C:13]([NH2:12])=[N:5][CH2:4]1

Participants

5

Reactant 3

HCID 5742Guanidine HydrochlorideHCID 10942334Sodium MethoxideHCID 17851079HCID 17851079, compound

Product 1

HCID 178510801314911-69-7

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a solution containing 6.7 g (41.6 mmol) of 2-methyl-1,3-propandiamine hydrochloride (Tetrahedron (1994) 50(29), 8617-8632) in 50 ml of methanol was added 83 ml of a solution of sodium methylate in methanol (1 mmol/ml) and the resulting mixture treated with 3.97 g (41.6 mmol) of guanidine hydrochloride.

Sources & evidence

ORD record
ord-50e4dc0b1ac642dcb37d17062880b6a9
Source dataset
uspto-grants-2008_12
Patent number
US07462621B2

Reaction notes

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