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Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]- → 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-N-methyl-benzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoic acid, 2-chloro-5-[(methylamino)sulfonyl]- | HCID 111724 | — |
| 反応物 | 1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone | HCID 685610 | — |
| 生成物 | 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-N-methyl-benzenesulfonamide | HCID 59793606 | — |
反応手順
The title compound was prepared according to the procedure D described for example 2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-Chloro-5-methylsulfamoyl-benzoic acid (CAS: 68901-09-7; BE 620741) (69%, light yellow foam, M−H: 452.1)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07462617B2 |
| 出典データセット | uspto-grants-2008_12 |
| ORD ID | ord-2a8e3826a79e4bec89008f8cf5fdbb82 |
| 出典メモ | uspto-grants-2008_12 |