HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 1-{4-[4-(2-Chloro-5-tetrazol-1-yl-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone | HCID 685610 | — |
| Reactant | 2-chloro-5-(1H-tetrazol-1-yl)benzoic acid | HCID 1129937 | — |
| Product | 1-{4-[4-(2-Chloro-5-tetrazol-1-yl-benzoyl)-piperazin-1-yl]-3-fluoro-phenyl}-ethanone | HCID 59853657 | — |
Reaction Steps
The title compound was prepared according to the procedure E described for example 2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-Chloro-5-tetrazol-1-yl-benzoic acid (CAS: 190270-10-1; commercial) (50%, white solid, M+H: 429.2)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462617B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-8c2281e24eee4a4a91728cc443b47990 |
| Source note | uspto-grants-2008_12 |