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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374261Generated: October 27, 2026

3-Fluoro-4-piperazin-1-yl-benzonitrile → 3-Fluoro-4-[4-(5-methanesulfonyl-2-thiazol-2-yl-benzoyl)-piperazin-1-yl]-benzonitrile

https://huagongshe.com/reaction/2374261

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-piperazin-1-yl-benzonitrileHCID 596113—
Reactant5-Methanesulfonyl-2-thiazol-2-yl-benzoic acidHCID 59853738—
Product3-Fluoro-4-[4-(5-methanesulfonyl-2-thiazol-2-yl-benzoyl)-piperazin-1-yl]-benzonitrileHCID 59853654—

Reaction Steps

The title compound was prepared according to the procedure E described for Example 9 from 3-Fluoro-4-piperazin-1-yl-benzonitrile [182181-38-0] and 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid (Example O). MS (ISP): 471.4 MH+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462617B2
Source datasetuspto-grants-2008_12
ORD IDord-76f6ba3b6b1040b7a26e25a04b942bb1
Source noteuspto-grants-2008_12