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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2374264Generated: October 30, 2026

1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine → [4-(2-Fluoro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(5-methanesulfonyl-2-thiazol-2-yl-phenyl)-methanone

https://huagongshe.com/reaction/2374264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazineHCID 46837495—
Reactant5-Methanesulfonyl-2-thiazol-2-yl-benzoic acidHCID 59853738—
Product[4-(2-Fluoro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(5-methanesulfonyl-2-thiazol-2-yl-phenyl)-methanoneHCID 59853693—

Reaction Steps

The title compound was prepared according to the procedure E described for Example 9 from 1-(2-Fluoro-4-trifluoromethyl-phenyl)-piperazine (Example F) and 5-Methanesulfonyl-2-thiazol-2-yl-benzoic acid (Example O). MS (ISP): 514.3 MH+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07462617B2
Source datasetuspto-grants-2008_12
ORD IDord-a79fbe60716b4dc1b38298e3f31ca663
Source noteuspto-grants-2008_12