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2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrimidine → (4-Methanesulfonyl-biphenyl-2-yl)-[4-(5-trifluoromethyl-pyrimidin-2-yl)-piperazin-1-yl]-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrimidine | HCID 16314797 | — |
| 反応物 | 4-(methylsulfonyl)-Biphenyl-2-carboxylic acid | HCID 57445254 | — |
| 生成物 | (4-Methanesulfonyl-biphenyl-2-yl)-[4-(5-trifluoromethyl-pyrimidin-2-yl)-piperazin-1-yl]-methanone | HCID 59853648 | — |
反応手順
The title compound was prepared according to the procedure E described for Example 9 from 2-Piperazin-1-yl-5-trifluoromethyl-pyrimidine (Example AE) and 4-Methanesulfonyl-biphenyl-2-carboxylic acid (Example V). MS (ISP): 431.1 MH+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07462617B2 |
| 出典データセット | uspto-grants-2008_12 |
| ORD ID | ord-da170cf44096452ea704c31f73c75063 |
| 出典メモ | uspto-grants-2008_12 |