HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 2-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-nitro-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone | HCID 685610 | — |
| Reactant | Methyl 4-nitrophthalate | HCID 19595681 | — |
| Product | 2-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-nitro-benzoic acid methyl ester | HCID 11293307 | — |
Reaction Steps
Following procedure D, the title compound is prepared by reaction of methyl 4-nitrophthalate [90072-77-8] with 1-(3fluoro-4-piperazin-1-yl-phenyl)-ethanone (m.p. 189-191° C., MS (ISP): 429.4 M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07462617B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-cb5ab680dc964eb2a4d956a52a7b6c71 |
| Source note | uspto-grants-2008_12 |